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Acute lymphoblastic leukaemia in infancy: experience in MRC UKALL trials. Report from the Medical Research Council Working Party on Childhood Leukaemia.

Abstract:

Acute lymphoblastic leukaemia (ALL) is rare under 1 year and has a poor prognosis. Only 14 of 48 infants treated on two consecutive MRC UKALL trials remain alive in first remission. Forty infants have subsequently been treated on a protocol incorporating further intensification with an option for high-dose chemotherapy and autologous or allogeneic bone marrow transplantation. The results show no improvement over previous trials largely due to the number of remission deaths; four of nine being...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Trial Service Unit
Role:
Author
Journal:
Leukemia
Volume:
8
Issue:
8
Pages:
1275-1279
Publication date:
1994-08-05
EISSN:
1476-5551
ISSN:
0887-6924
URN:
uuid:aa355f50-0deb-4138-a313-3d41e1283bd9
Source identifiers:
88522
Local pid:
pubs:88522

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