Thesis
Functional genomics of ankylosing spondylitis
- Abstract:
-
Ankylosing spondylitis (AS) is a chronic inflammatory arthritis primarily affecting the joints of the spine and pelvis. Its prevalence is highly correlated with the HLA-B*27 allele but not all of the genetic risk for this complex disease is explained by this association. At least 113 other susceptibility loci have been identified, with the NPEPPS locus implicated by multiple high impact studies.
This thesis aimed to fine-map the AS disease-associated signal that overlaps the NPEPP...
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Authors
Contributors
+ Knight, J
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Oxford college:
Merton College
Role:
Supervisor
ORCID:
0000-0002-0377-5536
+ Bowness, P
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Oxford college:
Merton College
Role:
Supervisor
+ Cohen, C
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Oxford college:
Merton College
Role:
Supervisor
+ Brown, M
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Oxford college:
Merton College
Role:
Supervisor
Funding
Versus Arthritis
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Bibliographic Details
- Type of award:
- MSc by Research
- Level of award:
- Masters
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- Keywords:
- Deposit date:
- 2020-12-28
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Terms of use
- Copyright holder:
- Midwinter, W
- Copyright date:
- 2020
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