Interaction of arousal states and low dose halothane on the acute hypercapnic ventilatory response in humans.

Journal article

The purpose of this study was to examine the effect of low dose halothane on the acute ventilatory response to hypercapnia, and to assess whether arousal (due to audiovisual (AV) stimulation or pain) modulates the response to halothane. Single step increases in end-tidal Pco(2) using dynamic end-tidal forcing were performed from eucapnia (end-tidal Pco(2) held 1 mmHg (0.13 kPa) above ambient) to hypercapnia (end-tidal Pco(2) 6 mmHg (0.79 kPa) above ambient) in eight healthy volunteers, with e...

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Authors: Pandit, J; Moreau, B

• Publication status: Published
• Journal: Anaesthesia
• Volume: 60
• Issue: 2
• Pages: 139-145
• Publication date: 2005-02-01
• DOI: 10.1111/j.1365-2044.2004.04037.x
• EISSN: 1365-2044
• ISSN: 0003-2409
• Language: English
• Keywords: Halothane; Pain; Hypercapnia; Arousal; Male; Anesthetics, Inhalation; Acoustic Stimulation; Humans; Female; Adult; Respiration; Photic Stimulation