Evaluation of serologic disease markers in a population-based cohort of patients with ulcerative colitis and Crohn's disease.

Journal article

BACKGROUND: The sensitivity of assays for antineutrophil cytoplasmic antibody (ANCA), anti-Saccharomyces cerevisiae antibody (ASCA), and antipancreatic antibody (PAB) in different laboratories is unknown. Likewise, the sensitivity and diagnostic usefulness of these assays in patients with inflammatory bowel disease (IBD) in the community is unknown. METHODS: An incidence cohort of 290 patients with IBD were offered participation in the study. Blood was obtained from 162 patients (56%) (83 wit...

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Authors: Sandborn, W; Loftus, E; Colombel, J; Fleming, K; Seibold, F

• Publication status: Published
• Journal: Inflammatory bowel diseases
• Volume: 7
• Issue: 3
• Pages: 192-201
• Publication date: 2001-08-01
• DOI: 10.1097/00054725-200108000-00003
• EISSN: 1536-4844
• ISSN: 1078-0998
• Language: English
• Keywords: Adolescent; Saccharomyces cerevisiae; Humans; Antibodies, Antineutrophil Cytoplasmic; Adult; Enzyme-Linked Immunosorbent Assay; Aged; Female; Male; Biological Markers; Crohn Disease; Antibodies, Fungal; Child; Cohort Studies; Logistic Models; Predictive Value of Tests; Sensitivity and Specificity; Middle Aged; Colitis, Ulcerative; Aged, 80 and over