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Pregabalin in fibromyalgia: meta-analysis of efficacy and safety from company clinical trial reports.

Abstract:

OBJECTIVES: Meta-analysis of pregabalin trials in FM using company trial reports, which provide more detailed information about trials than published papers. FM is a common condition with a significant impact on quality of life. METHODS: Reports of five high-quality randomized trials (3808 patients) of pregabalin in FM were obtained from Pfizer. Four trials (2754 patients) were of classical trial design and one was an enriched enrolment randomized withdrawal design. Outcomes for meta-analysi...

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Publication status:
Published

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Publisher copy:
10.1093/rheumatology/kep432

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
Journal:
Rheumatology (Oxford, England) More from this journal
Volume:
49
Issue:
4
Pages:
706-715
Publication date:
2010-04-01
DOI:
EISSN:
1462-0332
ISSN:
1462-0324
Language:
English
Keywords:
Pubs id:
pubs:346070
UUID:
uuid:aa1233c4-e9fb-462b-914e-c0931c384838
Local pid:
pubs:346070
Source identifiers:
346070
Deposit date:
2013-11-16

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