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Journal article

Modafinil for the treatment of fatigue in lung cancer: results of a placebo-controlled, double-blind, randomized trial

Abstract:

PURPOSE: Fatigue is a distressing symptom occurring in more than 60% of patients with cancer. The CNS stimulants modafinil and methylphenidate are recommended for the treatment of cancer-related fatigue, despite a limited evidence base. We aimed to evaluate the efficacy and tolerability of modafinil in the management of fatigue in patients with non-small-cell lung cancer (NSCLC). PATIENTS AND METHODS: Adults with advanced NSCLC and performance status of 0 to 2, who were not treated with chemo...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1200/JCO.2013.54.4346

Authors


Spathis, A More by this author
Blackhall, F More by this author
More by this author
Department:
Oxford, MSD, NDORMS, CSM
Bahadori, R More by this author
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Publisher:
American Society of Clinical Oncology Publisher's website
Journal:
Journal of Clinical Oncology Journal website
Volume:
32
Issue:
18
Pages:
1882-1888
Publication date:
2014-06-05
DOI:
ISSN:
1527-7755 and 0732-183X
Pubs id:
pubs:463015
URN:
uri:aa113894-a576-4337-94d5-76cc72365f98
UUID:
uuid:aa113894-a576-4337-94d5-76cc72365f98
Local pid:
pubs:463015
Paper number:
18

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