Thesis
The role of histone 3 lysine 27 trimethylation in thymic epithelial cell development and function
- Abstract:
-
Thymic epithelial cells (TEC) create the unique environment for the selection of T cells that are tolerant to self but reactive to foreign antigens. For this purpose, TEC express an almost comprehensive repertoire of self-antigens, through a process referred to as promiscuous gene expression (PGE). The precise molecular mechanisms that account for PGE remain incompletely defined although a subset of promiscuously expressed genes rely for their efficient expression on the presence of t...
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Funding
+ Swiss National Science Foundation
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Funding agency for:
Graedel, A
Grant:
P1SKP3_174877
Bibliographic Details
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- UUID:
-
uuid:aa106554-b722-4bf3-9d27-d0bf15850947
- Deposit date:
- 2019-06-18
Terms of use
- Copyright holder:
- Graedel, A
- Copyright date:
- 2018
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