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Improving quinolone use in hospitals by using a bundle of interventions in an interrupted time series analysis.

Abstract:

The objectives of the present study were to determine the effects of multiple targeted interventions on the level of use of quinolones and the observed rates of resistance to quinolones in Escherichia coli isolates from hospitalized patients. A bundle consisting of four interventions to improve the use of quinolones was implemented. The outcome was measured from the monthly levels of use of intravenous (i.v.) and oral quinolones and the susceptibility patterns for E. coli isolates from hospit...

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Publication status:
Published

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Publisher copy:
10.1128/aac.01581-09

Authors


Willemsen, I More by this author
van Buitenen, C More by this author
Winters, M More by this author
Andriesse, G More by this author
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Journal:
Antimicrobial agents and chemotherapy
Volume:
54
Issue:
9
Pages:
3763-3769
Publication date:
2010-09-05
DOI:
EISSN:
1098-6596
ISSN:
0066-4804
URN:
uuid:aa0f5f31-eddf-4d7e-9dc4-4e6bef77f600
Source identifiers:
223865
Local pid:
pubs:223865

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