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Serum inhibitors of leukocyte chemotaxis in Crohn's disease and ulcerative colitis.

Abstract:

Studies were undertaken to determine the incidence and nature of serum chemotaxis inhibitors in patients with Crohn's disease and ulcerative colitis. Sera from patients with active Crohn's disease were shown to contain chemotactic factor-directed inhibitory activity. The molecular size of the inhibitor estimated by gel filtration is similar to the 7S gamma-globulins and it is precipitable by 40% ammonium sulfate. Less marked inhibitory activity is present in the same fractions of sera from pa...

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Publication status:
Published

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Journal:
Gastroenterology
Volume:
82
Issue:
6
Pages:
1327-1334
Publication date:
1982-06-05
EISSN:
1528-0012
ISSN:
0016-5085
URN:
uuid:aa050ba5-101b-4973-9cfd-bcf2a92b511e
Source identifiers:
165803
Local pid:
pubs:165803

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