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Journal article

The magnitude and kinetics of the mucosal HIV-specific CD8+ T lymphocyte response and virus RNA load in breast milk

Abstract:

Background: The risk of postnatal HIV transmission is associated with the magnitude of the milk virus load. While HIV-specific cellular immune responses control systemic virus load and are detectable in milk, the contribution of these responses to the control of virus load in milk is unknown. Methods: We assessed the magnitude of the immunodominant GagRY11 and subdominant EnvKY9-specific CD8+ T lymphocyte response in blood and milk of 10 A*3002+, HIV-infected Malawian women throughout the per...

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Journal:
PLoS ONE More from this journal
Volume:
6
Issue:
8
Publication date:
2011-08-23
DOI:
EISSN:
1932-6203
Language:
English
Pubs id:
pubs:179536
UUID:
uuid:aa042dca-1811-4bf5-a7a3-627e22785e4d
Local pid:
pubs:179536
Source identifiers:
179536
Deposit date:
2012-12-19

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