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Journal article

TNFalpha-stimulated gene product (TSG-6) and its binding protein, IalphaI, in the human intervertebral disc: new molecules for the disc.

Abstract:

Inflammation and irritation of the nerve roots has been indicated as an important factor in the pain associated with symptomatic disc herniations. Tumour necrosis factor alpha (TNFalpha) is now believed to be involved in this pathway. TNFalpha causes connective tissue cells in culture to synthesise a glycoprotein, TNFalpha-stimulated gene-6 (TSG-6). TSG-6 is found in inflammatory diseases of related connective tissues, such as articular cartilage in rheumatoid arthritis, but is not present in...

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Publication status:
Published

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Publisher copy:
10.1007/s00586-004-0798-x

Authors


Roberts, S More by this author
Bayliss, MT More by this author
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Journal:
European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
Volume:
14
Issue:
1
Pages:
36-42
Publication date:
2005-02-05
DOI:
EISSN:
1432-0932
ISSN:
0940-6719
URN:
uuid:a9f34122-71ba-486d-95be-77edee078781
Source identifiers:
238364
Local pid:
pubs:238364

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