Journal article
Fetal liver blood flow distribution: role in human developmental strategy to prioritize fat deposition versus brain development
- Abstract:
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Among primates, human neonates have the largest brains but also the highest proportion of body fat. If placental nutrient supply is limited, the fetus faces a dilemma: should resources be allocated to brain growth, or to fat deposition for use as a potential postnatal energy reserve? We hypothesised that resolving this dilemma operates at the level of umbilical blood distribution entering the fetal liver. In 381 uncomplicated pregnancies in third trimester, we measured blood flow perfusing th...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Version of record, pdf, 480.4KB)
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- Publisher copy:
- 10.1371/journal.pone.0041759
Authors
Bibliographic Details
- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PLoS ONE Journal website
- Volume:
- 7
- Issue:
- 8
- Pages:
- e41759
- Publication date:
- 2012-08-22
- Acceptance date:
- 2012-06-25
- DOI:
- EISSN:
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1932-6203
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:349831
- UUID:
-
uuid:a9db0be9-0da7-43c2-bb14-a333a778f2c2
- Local pid:
- pubs:349831
- Source identifiers:
-
349831
- Deposit date:
- 2013-11-16
Terms of use
- Copyright holder:
- Godfrey et al
- Copyright date:
- 2012
- Notes:
- © Godfrey et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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