Journal article
Computational methods for generating models of denatured and partially folded proteins.
- Abstract:
-
Partially folded and denatured proteins can give important insights into protein folding, misfolding, and aggregation. Such non-native states of proteins are however very difficult to characterise in detail as they are dynamic, heterogeneous systems comprising of ensembles of interconverting conformers. This article describes methods that produce models for non-native proteins in atomic detail. A variety of molecular dynamics based protocols are discussed together with some recent procedures ...
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- Publication status:
- Published
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- Publisher copy:
- 10.1016/j.ymeth.2004.03.011
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Authors
Bibliographic Details
- Journal:
- Methods (San Diego, Calif.)
- Volume:
- 34
- Issue:
- 1
- Pages:
- 144-150
- Publication date:
- 2004-09-05
- DOI:
- EISSN:
-
1095-9130
- ISSN:
-
1046-2023
- URN:
-
uuid:a9cc39ba-31da-43a4-aada-6dd9eea509e8
- Source identifiers:
-
32804
- Local pid:
- pubs:32804
Item Description
- Language:
- English
- Keywords:
Terms of use
- Copyright date:
- 2004
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