Recent advances in understanding of the DNA double-strand break repair machinery of plants.

Journal article

Living cells suffer numerous and varied alterations of their genetic material. Of these, the DNA double-strand break (DSB) is both particularly threatening and common. Double-strand breaks arise from exposure to DNA damaging agents, but also from cell metabolism-in a fortuitous manner during DNA replication or repair of other kinds of lesions and in a programmed manner, for example during meiosis or V(D)J gene rearrangement. Cells possess several overlapping repair pathways to deal with these...

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Authors: Bleuyard, J; Gallego, M; White, C

• Journal: DNA repair
• Volume: 5
• Issue: 1
• Pages: 1-12
• Publication date: 2006-01-01
• DOI: 10.1016/j.dnarep.2005.08.017
• EISSN: 1568-7856
• ISSN: 1568-7864
• Language: English
• Keywords: DNA; Recombination, Genetic; DNA-Binding Proteins; Multiprotein Complexes; Arabidopsis Proteins; Rec A Recombinases; Plants; DNA Repair; Cell Cycle Proteins; Rad51 Recombinase; Adenosine Triphosphatases; DNA Damage; BRCA2 Protein