Journal article
Low-dose tryptophan depletion in recovered depressed patients induces changes in cognitive processing without depressive symptoms
- Abstract:
-
Background: Acute tryptophan depletion can induce a transient reappearance of depressive symptoms in recovered depressed patients. The neurochemical mechanism if thought to be impairment of brain serotonin neurotransmission, but the neuropsychologic mechanisms underlying the effect are unclear. Methods: To assess whether low-dose tryptophan depletion can tease out the psychological mechanisms sensitive to substrate depletion in vulnerable subjects without inducing mood changes, a between-subj...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Funding
Merck, Sharpe and Dohme, Harlow, UK
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Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- Biological Psychiatry Journal website
- Volume:
- 57
- Issue:
- 5
- Pages:
- 517-524
- Publication date:
- 2005-03-01
- DOI:
- ISSN:
-
0006-3223
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:a9ba4157-75c6-420b-a8bc-a465d0f7bf8d
- Local pid:
- ora:4185
- Deposit date:
- 2010-09-17
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Terms of use
- Copyright holder:
- Society of Biological Psychiatry
- Copyright date:
- 2005
- Notes:
- The full-text of this article is not currently available in ORA, but you may be able to access the article via the publisher copy link on this record page.
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