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Journal article

Agile CD22 nanoclusters run rings around fenced BCR

Abstract:

B lymphocytes are key players in host defence, but also autoimmune diseases. Their survival depends upon tonic signals transduced by surface immunoglobulin (BCR) and the process leading to antibody secretion is initiated by interaction of BCR with a cognate antigen. CD22 limits signalling of the BCR to strike a balance between tonic signalling, reactivity to pathogens and prevention of autoimmunity. In this issue, Gasparrini et al (2016) combined super‐resolution imaging approaches with singl...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.15252/embj.201593745

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Kennedy Institute for Rheumatology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Kennedy Institute for Rheumatology
Role:
Author
Publisher:
EMBO Press
Journal:
EMBO Journal More from this journal
Volume:
35
Issue:
3
Pages:
237-238
Publication date:
2016-01-08
DOI:
EISSN:
1460-2075
ISSN:
0261-4189
Language:
English
Pubs id:
pubs:587032
UUID:
uuid:a9ba0aac-f3a8-4c56-8729-29ebda2c3782
Local pid:
pubs:587032
Source identifiers:
587032
Deposit date:
2016-03-30

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