A functional magnetic resonance imaging study of verbal working memory in young people at increased familial risk of depression.
BACKGROUND: Patients with depression show abnormalities in the neural circuitry supporting working memory. These abnormalities apparently persist into clinical remission, raising the possibility that they might be trait markers indicating vulnerability to depression. METHODS: We studied 17 young people who had a depressed parent but no personal history of depressive illness (FH) and 15 healthy control subjects with no family history of depression. Participants performed a verbal working memor...Expand abstract
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