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A functional magnetic resonance imaging study of verbal working memory in young people at increased familial risk of depression.

Abstract:

BACKGROUND: Patients with depression show abnormalities in the neural circuitry supporting working memory. These abnormalities apparently persist into clinical remission, raising the possibility that they might be trait markers indicating vulnerability to depression. METHODS: We studied 17 young people who had a depressed parent but no personal history of depressive illness (FH) and 15 healthy control subjects with no family history of depression. Participants performed a verbal working memor...

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Publication status:
Published

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Authors


Mannie, ZN More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
Journal:
Biological psychiatry
Volume:
67
Issue:
5
Pages:
471-477
Publication date:
2010-03-05
DOI:
EISSN:
1873-2402
ISSN:
0006-3223
URN:
uuid:a9b2659d-a782-4a2e-adf4-9681178b9525
Source identifiers:
139398
Local pid:
pubs:139398

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