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Effect of mild hyperglycemia +/- meta-iodo-benzylguanidine on the radiation response of R3230 Ac tumors.

Abstract:

The effects of glucose or meta-iodo-benzylguanidine (MIBG) on oxygen utilization (QO2) of several tumor cell lines were studied using a Clark-type electrode chamber. For in vivo studies, rats bearing R3230 Ac rat mammary adenocarcinomas were utilized. To evaluate changes in tumor oxygenation induced by glucose or MIBG, intratumoral pO2 and skeletal muscle pO2 were measured using Eppendorf Histography. To find the effect of mild hyperglycemia (i.p., 1 g/kg) +/- MIBG (i.p., 20 mg/kg) on the rad...

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Publication status:
Published

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Journal:
Advances in experimental medicine and biology
Volume:
530
Pages:
177-186
Publication date:
2003-01-01
ISSN:
0065-2598
Source identifiers:
118198
Language:
English
Keywords:
Pubs id:
pubs:118198
UUID:
uuid:a9b0031f-ae43-4f39-9e45-ef653bf64193
Local pid:
pubs:118198
Deposit date:
2012-12-19

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