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Prognostic significance of a novel hypoxia-regulated marker, carbonic anhydrase IX, in invasive breast carcinoma.

Abstract:

PURPOSE: To assess the frequency of expression and the prognostic significance of a hypoxia-regulated marker, carbonic anhydrase IX (CA IX), in a cohort of patients with invasive breast cancer. PATIENTS AND METHODS: CA IX expression was evaluated by immunohistochemistry with a murine monoclonal antibody, M75, in a series of 103 women treated surgically for invasive breast cancer. The majority of patients were treated with adjuvant hormonal or chemotherapy. The frequency of CA IX expression, i...

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Publication status:
Published

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Journal:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology More from this journal
Volume:
19
Issue:
16
Pages:
3660-3668
Publication date:
2001-08-01
EISSN:
1527-7755
ISSN:
0732-183X

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