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Intrahepatic Lipid Content and Insulin Resistance Are More Strongly Associated with Impaired NEFA Suppression after Oral Glucose Loading Than with Fasting NEFA Levels in Healthy Older Individuals

Abstract:

Introduction. The mechanisms underlying the association between insulin resistance and intrahepatic lipid (IHL) accumulation are not completely understood. We sought to determine whether this association was explained by differences in fasting non-esterified fatty acid (NEFA) levels and/or NEFA suppression after oral glucose loading. Materials and Methods. We performed a cross-sectional analysis of 70 healthy participants in the Hertfordshire Physical Activity Trial (39 males, age 71.3 ± 2.4 ...

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Publication status:
Published

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Publisher copy:
10.1155/2013/870487

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Journal:
INTERNATIONAL JOURNAL OF ENDOCRINOLOGY More from this journal
Volume:
2013
Pages:
1-7
Publication date:
2013-01-01
DOI:
EISSN:
1687-8345
ISSN:
1687-8337
Language:
English
Pubs id:
pubs:406066
UUID:
uuid:a9aa2947-d487-41bc-b961-9853c0217909
Local pid:
pubs:406066
Source identifiers:
406066
Deposit date:
2013-11-17

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