Journal article
Polycomb repressive complex 1 shapes the nucleosome landscape but not accessibility at target genes
- Abstract:
-
Polycomb group (PcG) proteins are transcriptional repressors that play important roles regulating gene expression during animal development. In vitro experiments have shown that PcG protein complexes can compact chromatin to limit the activity of chromatin remodelling enzymes and access of the transcriptional machinery to DNA. In fitting with these ideas, gene promoters associated with PcG proteins have been reported to be less accessible than other gene promoters. However, it remains largely...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Funding
European Research Council
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Wellcome Trust
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Lister Institute of Preventive
Medicine
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Bibliographic Details
- Publisher:
- Cold Spring Harbor Laboratory Press Publisher's website
- Journal:
- Genome Research Journal website
- Volume:
- 28
- Pages:
- 1494-1507
- Publication date:
- 2018-08-28
- Acceptance date:
- 2018-08-27
- DOI:
- EISSN:
-
1549-5469
- ISSN:
-
1088-9051
Item Description
- Keywords:
- Pubs id:
-
pubs:896518
- UUID:
-
uuid:a9a67f1f-9702-42b5-ad41-a392637f53f1
- Local pid:
- pubs:896518
- Deposit date:
- 2018-08-28
Terms of use
- Copyright holder:
- King et al
- Copyright date:
- 2018
- Notes:
- This article, published in Genome Research, is available under a Creative Commons License (Attribution-NonCommercial 4.0 International license), as described at http://creativecommons.org/licenses/by-nc/4.0/.
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