Journal article
Different mechanisms underlie the long‐term regulation of pyruvate dehydrogenase kinase (PDHK) by tri‐iodothyronine in heart and liver
- Abstract:
-
Antibodies to purified recombinant PDHKII were used for ELISAs of PDHKII in mitochondrial extracts. In liver, hyperthyroidism elicited a 2.3‐fold increase in PDHK activity (P<0.01) which was accompanied by a significant 1.5‐fold (P<0.001) increase in the amount of mitochondrial immunoreactive PDHKII. In contrast, despite a stable 2.0‐fold increase in cardiac PDHK activity (P<0.001), the amount of mitochondrial immunoreactive PDHKII in heart was unaffected by hyperthyroidism. The mech...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Bibliographic Details
- Publisher:
- Wiley Publisher's website
- Journal:
- FEBS Letters Journal website
- Volume:
- 419
- Issue:
- 1
- Pages:
- 55-57
- Publication date:
- 1997-12-08
- DOI:
- EISSN:
-
1873-3468
- ISSN:
-
0014-5793
Item Description
- Keywords:
- Pubs id:
-
pubs:673833
- UUID:
-
uuid:a9a19c94-c30c-402e-8dd5-2cbc5fa47adf
- Local pid:
- pubs:673833
- Source identifiers:
-
673833
- Deposit date:
- 2017-01-30
Terms of use
- Copyright holder:
- Federation of European Biochemical Societies
- Copyright date:
- 1997
- Notes:
- © 1997 Federation of European Biochemical Societies/
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