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Integrative biochemical, proteomics and metabolomics cerebrospinal fluid biomarkers predict clinical conversion to multiple sclerosis

Abstract:

Eighty-five percent of multiple sclerosis cases begin with a discrete attack termed clinically isolated syndrome, but 37% of clinically isolated syndrome patients do not experience a relapse within 20 years of onset. Thus, the identification of biomarkers able to differentiate between individuals who are most likely to have a second clinical attack from those who remain in the clinically isolated syndrome stage is essential to apply a personalized medicine approach. We sought to identi...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/braincomms/fcab084

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Role:
Author
ORCID:
0000-0002-8580-2023
More by this author
Role:
Author
ORCID:
0000-0002-3538-621X
Publisher:
Oxford University Press Publisher's website
Journal:
Brain Communications Journal website
Volume:
3
Issue:
2
Article number:
fcab084
Publication date:
2021-04-19
Acceptance date:
2021-03-19
DOI:
EISSN:
2632-1297
Language:
English
Keywords:
Pubs id:
1177224
Local pid:
pubs:1177224
Deposit date:
2021-05-27

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