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Journal article

The (gradual) rise of memory inflation

Abstract:

Memory inflation, as a term, has been used for 15 years now to describe the longitudinal development of stable, expanded CD8+ T memory pools with a distinct phenotype and functional profile which emerge in specific infection and vaccine settings. These settings have in common the persistence of antigen, especially cytomegalovirus infection but also more recently adenoviral vector vaccination. However, in contrast to chronic infections which lead to “exhaustion” the repeated antigen encounters...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1111/imr.12653

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Oxford college:
Green Templeton College
Role:
Author
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Name:
National Institute for Health Research
Grant:
NF-SI-0515-10005
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Name:
Wellcome Trust
Grant:
Investigator award WT109965MA
Publisher:
John Wiley & Sons Ltd
Journal:
Immunological Reviews More from this journal
Volume:
283
Issue:
1
Pages:
99-112
Publication date:
2018-04-17
Acceptance date:
2018-03-08
DOI:
ISSN:
1600-065X
Keywords:
Pubs id:
pubs:828424
UUID:
uuid:a98d9717-d70e-4f35-b944-9005ba8bd6d7
Local pid:
pubs:828424
Deposit date:
2018-03-08

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