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Dictyostelium discoideum: cellular self-organization in an excitable biological medium.

Abstract:

The dynamics which govern the establishment of pattern and form in multicellular organisms remain a key problem of developmental biology. We study this question in the case of morphogenesis during aggregation of the slime mould Dictyostelium discoideum. Here detailed experimental information allows the formulation of a mechanistic model in which the central element is the coupling of the previously much-studied intracellular cyclic AMP signalling with the chemotactic cell response in cyclic A...

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Publication status:
Published

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Publisher copy:
10.1098/rspb.1995.0037

Authors


Sherratt, JA More by this author
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Institution:
University of Oxford
Department:
Oxford, MPLS, Mathematical Inst
Journal:
Proceedings. Biological sciences / The Royal Society
Volume:
259
Issue:
1356
Pages:
249-257
Publication date:
1995-03-05
DOI:
EISSN:
1471-2954
ISSN:
0962-8452
URN:
uuid:a98c6334-1a51-4d70-a06c-f83135b0dae7
Source identifiers:
23785
Local pid:
pubs:23785

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