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Thesis

Molecular assembly and interactions of membrane proteins and viral glycoproteins using mass photometry

Abstract:

Integral membrane proteins (IMPs) and their interactions form the basis underlying many processes essential for life of all living organisms. Despite their pivotal importance, they are challenging to study due to the presence of a bilayer-embedded transmembrane domain requiring astute strategies to achieve solubilisation in aqueous environments. Here we present mass photometry as a novel technique to investigate IMPs and their interactions in a variety of membrane mimetic systems, uncoveri...

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Division:
MPLS
Department:
Chemistry
Sub department:
Physical & Theoretical Chem
Oxford college:
St John's College
Role:
Author
ORCID:
https://orcid.org/0000-0002-0358-4262

Contributors

Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Physical & Theoretical Chem
Research group:
Kukura group
Oxford college:
Exeter College
Role:
Supervisor
ORCID:
0000-0003-0136-7704
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Role:
Supervisor
Division:
MPLS
Department:
Chemistry
Role:
Supervisor
Division:
MPLS
Department:
Plant Sciences
Role:
Examiner
ORCID:
0000-0003-4346-182X
Institution:
King's College London
Role:
Examiner
More from this funder
Name:
Engineering and Physical Sciences Research Council
Programme:
Centre for Doctoral Training in Systems Biology
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
DOI:

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