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Cost-effectiveness of intrapleural use of tissue plasminogen activator and DNase in pleural infection: Evidence from the MIST2 randomised controlled trial.

Abstract:

The MIST2 trial showed that combined intrapleural use of tissue plasminogen activator (t-PA) and DNase was effective when compared to single agents or placebo. However, the treatment costs are significant and overall cost-effectiveness of combined therapy remains unclear.An economic evaluation of the MIST2 trial was performed to assess the cost-effectiveness of combined therapy. Costs included were those related to study medications, initial hospital stay, and subsequent hospitalisations. Out...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1183/13993003.01550-2018

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Role:
Author
ORCID:
0000-0002-2118-2662
Publisher:
European Respiratory Society Publications
Journal:
European respiratory journal More from this journal
Volume:
54
Issue:
2019
Article number:
1801550
Publication date:
2019-05-16
Acceptance date:
2019-05-01
DOI:
EISSN:
1399-3003
ISSN:
0903-1936
Pmid:
31097519
Language:
English
Pubs id:
pubs:999408
UUID:
uuid:a959ef24-0ec4-45c6-99d5-885d7af6eef5
Local pid:
pubs:999408
Source identifiers:
999408
Deposit date:
2019-05-27

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