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Potential for diagnosis of infectious disease from the 100,000 Genomes Project Metagenomic Dataset: recommendations for reporting results

Abstract:

The identification of microbiological infection is usually a diagnostic investigation, a complex process that is firstly initiated by clinical suspicion. With the emergence of high-throughput sequencing (HTS) technologies, metagenomic analysis has unveiled the power to identify microbial DNA/RNA from a diverse range of clinical samples (1). Metagenomic analysis of whole human genomes at the clinical/research interface bypasses the steps of clinical scrutiny and targeted testing and has the po...

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Publication status:
Published
Peer review status:
Peer reviewed

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Role:
Author
ORCID:
0000-0002-0141-4753
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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Subgroup:
NDM Experimental Medicine
Role:
Author
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Publisher:
F1000Research Publisher's website
Journal:
Wellcome Open Research Journal website
Volume:
4
Article number:
155
Publication date:
2019-10-14
Acceptance date:
2019-10-07
DOI:
EISSN:
2398-502X
ISSN:
2398-502X
Pmid:
32055707
Pubs id:
1088074
Local pid:
pubs:1088074
Language:
English
Keywords:
Format:
Electronic-eCollection

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