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Journal article

Comparative evaluation of label-free SINQ normalized spectral index quantitation in the central proteomics facilities pipeline.

Abstract:

Normalized spectral index quantification was recently presented as an accurate method of label-free quantitation, which improved spectral counting by incorporating the intensities of peptide MS/MS fragment ions into the calculation of protein abundance. We present SINQ, a tool implementing this method within the framework of existing analysis software, our freely available central proteomics facilities pipeline (CPFP). We demonstrate, using data sets of protein standards acquired on a variety...

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Publication status:
Published

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Publisher copy:
10.1002/pmic.201000800

Authors


Trudgian, DC More by this author
Ridlova, G More by this author
Fischer, R More by this author
Mackeen, MM More by this author
Ternette, N More by this author
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Journal:
Proteomics
Volume:
11
Issue:
14
Pages:
2790-2797
Publication date:
2011-07-05
DOI:
EISSN:
1615-9861
ISSN:
1615-9853
URN:
uuid:a940dc21-ad0d-4d9c-912c-3b927d78593d
Source identifiers:
151227
Local pid:
pubs:151227

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