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Journal article

New cell lines from mouse epiblast share defining features with human embryonic stem cells.

Abstract:

The application of human embryonic stem (ES) cells in medicine and biology has an inherent reliance on understanding the starting cell population. Human ES cells differ from mouse ES cells and the specific embryonic origin of both cell types is unclear. Previous work suggested that mouse ES cells could only be obtained from the embryo before implantation in the uterus. Here we show that cell lines can be derived from the epiblast, a tissue of the post-implantation embryo that generates the em...

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Publication status:
Published

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Publisher copy:
10.1038/nature05972

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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
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Journal:
Nature
Volume:
448
Issue:
7150
Pages:
196-199
Publication date:
2007-07-01
DOI:
EISSN:
1476-4687
ISSN:
0028-0836
Source identifiers:
55530
Language:
English
Keywords:
Pubs id:
pubs:55530
UUID:
uuid:a93632fb-9f5e-4fbf-bc9f-15ff817b603e
Local pid:
pubs:55530
Deposit date:
2012-12-19

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