Journal article
Filamentous influenza viruses
- Abstract:
- Clinical isolates of influenza virus produce pleomorphic virus particles, including extremely long filamentous virions. In contrast, strains of influenza that have adapted to laboratory growth typically produce only spherical virions. As a result, the filamentous phenotype has been overlooked in most influenza virus research. Recent advances in imaging and improved animal models have highlighted the distinct structure and functional relevance of filamentous virions. In this review we summarise what is currently known about these strikingly elongated virus particles and discuss their possible roles in clinical infections.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Preview, Accepted manuscript, pdf, 710.1KB, Terms of use)
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- Publisher copy:
- 10.1099/jgv.0.000535
Authors
+ Medical Research Council
More from this funder
- Funding agency for:
- Fodor, E
- Hutchinson, E
- Grant:
- MR/K000241/1
- Career Development Award [MR/N008618/1
+ Wellcome Trust
More from this funder
- Funding agency for:
- Dadonaite, B
- Grant:
- Studentship [105399/Z/14/Z
- Publisher:
- Microbiology Society
- Journal:
- Journal of General Virology More from this journal
- Publication date:
- 2016-06-30
- Acceptance date:
- 2016-06-28
- DOI:
- EISSN:
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1465-2099
- ISSN:
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0022-1317
- Pubs id:
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pubs:631624
- UUID:
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uuid:a925f2a8-44e8-436e-b3b3-6d065e642443
- Local pid:
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pubs:631624
- Source identifiers:
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631624
- Deposit date:
-
2016-07-04
Terms of use
- Copyright holder:
- Dadonaite et al
- Copyright date:
- 2016
- Notes:
- Author(s) retain copyright; published by the Microbiology Society under license.
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