Journal article icon

Journal article

Extending methods for investigating the relationship between treatment effect and baseline risk from pairwise meta-analysis to network meta-analysis

Abstract:

Baseline risk is a proxy for unmeasured but important patient‐level characteristics, which may be modifiers of treatment effect, and is a potential source of heterogeneity in meta‐analysis. Models adjusting for baseline risk have been developed for pairwise meta‐analysis using the observed event rate in the placebo arm and taking into account the measurement error in the covariate to ensure that an unbiased estimate of the relationship is obtained. Our objective is to extend these methods to ...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1002/sim.5539
Publication website:
https://onlinelibrary.wiley.com/doi/abs/10.1002/sim.5539

Authors


More by this author
Division:
MSD
Sub department:
Primary Care Health Sciences
Role:
Author
Publisher:
Wiley
Journal:
Statistics in Medicine More from this journal
Volume:
32
Issue:
5
Pages:
752-771
Publication date:
2012-08-02
DOI:
EISSN:
1097-0258
ISSN:
0277-6715
Language:
English
Keywords:
Pubs id:
1118299
Local pid:
pubs:1118299
Deposit date:
2020-07-10

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP