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Bisphosphonates: Mechanisms of Action

Abstract:

The bisphosphonates are a class of drugs used in various diseases of calcium metabolism. This chapter describes the history of the development, chemistry, biological actions, and molecular mechanisms of action of bisphosphonates. It also highlights the newer developments in the field of study of bisphosphonates. Great progress has been made over the past two decades in understanding the mechanism of action of the bisphosphonates. Bisphosphonates are widely used in the treatment of osteoporosi...

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Publisher:
Elsevier Inc.
Volume:
2
Pages:
1737-1767
Publication date:
2008-01-01
DOI:
URN:
uuid:a8f2461c-6260-441b-81a2-8c8c6b66dd87
Source identifiers:
426478
Local pid:
pubs:426478
Language:
English

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