Journal article
Viral macro domains reverse protein ADP-ribosylation.
- Abstract:
-
ADP-ribosylation is a posttranslational protein modification in which ADP-ribose is transferred from NAD+ to specific acceptors to regulate a wide variety of cellular processes. The macro domain is an ancient and highly evolutionarily conserved protein domain widely distributed throughout all kingdoms of life, including viruses. The human TARG1/C6orf130, MacroD1, and MacroD2 proteins can reverse ADP-ribosylation by acting on ADP-ribosylated substrates through the hydrolytic activity of their ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Funding
Flanders Fund for Scientific Research
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Wellcome Trust
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European Research Council
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Bibliographic Details
- Publisher:
- American Society for Microbiology Publisher's website
- Journal:
- Journal of Virology Journal website
- Volume:
- 90
- Issue:
- 19
- Pages:
- 8478-8486
- Publication date:
- 2016-07-01
- Acceptance date:
- 2016-07-05
- DOI:
- ISSN:
-
0022-538X and 1098-5514
- Pmid:
-
27440879
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:636441
- UUID:
-
uuid:a8f05972-f2d5-4d20-bfef-e74050a5eb30
- Local pid:
- pubs:636441
- Source identifiers:
-
636441
- Deposit date:
- 2016-09-21
Terms of use
- Copyright holder:
- American Society for Microbiology
- Copyright date:
- 2016
- Notes:
- Copyright © 2016, American Society for Microbiology. All Rights Reserved.
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