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Journal article

Functional subsets of human helper-inducer cells defined by a new monoclonal antibody, UCHL1.

Abstract:

The monoclonal antibody UCHL1 identified an antigen present on most thymocytes, a subpopulation of resting T cells within both the CD4 and CD8 subsets, and on mature activated T cells. The UCHL1 determinant is also present on cells of the myeloid lineage, but not normal B cells or NK cells. Functionally, UCHL1 identifies a subpopulation of T cells which proliferates maximally to soluble antigen and provides maximum help for PWM-stimulated immunoglobulin synthesis. In contrast, the UCHL1- cell...

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
Journal:
Immunology
Volume:
58
Issue:
1
Pages:
63-70
Publication date:
1986-05-01
EISSN:
1365-2567
ISSN:
0019-2805
Source identifiers:
35154
Language:
English
Keywords:
Pubs id:
pubs:35154
UUID:
uuid:a8e4fc7c-b074-4c5c-86b4-cc32ec70eeee
Local pid:
pubs:35154
Deposit date:
2012-12-20

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