Journal article icon

Journal article

Proteomics profiling of interactome dynamics by colocalisation analysis (COLA)

Abstract:

Localisation and protein function are intimately linked in eukaryotes, as proteins are localised to specific compartments where they come into proximity of other functionally relevant proteins. Significant co-localisation of two proteins can therefore be indicative of their functional association. We here present COLA, a proteomics based strategy coupled with a bioinformatics framework to detect protein-protein co-localisations on a global scale. COLA reveals functional interactions by matchi...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Authors


More by this author
Division:
MPLS
Department:
Engineering Science
Sub department:
Engineering Science
Role:
Author
More by this author
Role:
Author
ORCID:
0000-0002-5478-0503
More by this author
Role:
Author
ORCID:
0000-0003-4712-2737
More from this funder
Name:
Cancer Research UK
Grant:
16512
Publisher:
Royal Society of Chemistry
Journal:
Molecular bioSystems More from this journal
Volume:
13
Issue:
1
Pages:
92-105
Place of publication:
England
Publication date:
2016-11-01
Acceptance date:
2016-11-01
DOI:
EISSN:
1742-2051
ISSN:
1742-206X
Pmid:
27824369
Language:
English
Keywords:
Pubs id:
699397
Local pid:
pubs:699397
Deposit date:
2020-03-17

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP