- Abstract:
-
CD59 is a membrane-bound glycoprotein that protects host cells from lysis by inhibiting the terminal pathway of complement, preventing the formation and insertion of the membrane attack complex (MAC). Crystals of bacterially expressed and nonglycosylated recombinant soluble human CD59 have been obtained from three crystallization conditions, each of which gave rise to a distinct crystal form. Each crystal form led to a crystal structure at high resolution (1.15, 1.35 and 1.8 Å). In one of the...
Expand abstract - Publisher copy:
- 10.1107/S1744309107033477
-
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- Journal:
- Acta Crystallographica Section F: Structural Biology and Crystallization Communications
- Volume:
- 63
- Issue:
- 8
- Pages:
- 648-652
- Publication date:
- 2007-07-28
- DOI:
- EISSN:
-
1744-3091
- ISSN:
-
1744-3091
- URN:
-
uuid:a8d33075-6713-4bd8-b685-8791960cbb51
- Source identifiers:
-
148432
- Local pid:
- pubs:148432
- Language:
- English
- Keywords:
- Copyright date:
- 2007
Journal article
High-resolution structures of bacterially expressed soluble human CD59
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