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Unsupervised primaquine for the treatment of Plasmodium vivax malaria relapses in southern Papua: A hospital-based cohort study

Abstract:

Background: Primaquine is the only licensed drug for eradicating Plasmodium vivax hypnozoites and, therefore, preventing relapses of vivax malaria. It is a vital component of global malaria elimination efforts. Primaquine is efficacious when supervised in clinical trials, but its effectiveness in real-world settings is unknown. We aimed to determine whether unsupervised primaquine was effective for preventing re-presentation to hospital with vivax malaria in southern Papua, Indonesia.

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1371/journal.pmed.1002379

Authors


Contributors

Role:
Editor
More from this funder
Funding agency for:
Price, RN
Poespoprodjo, JR
Grant:
GNT1037304
099875
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Funding agency for:
Anstey, NM
Simpson, JA
Price, RN
Grant:
1042072
1104975
GNT1037304
More from this funder
Funding agency for:
Douglas, NM
Publisher:
Public Library of Science Publisher's website
Journal:
PLoS Medicine Journal website
Volume:
14
Issue:
8
Pages:
e1002379
Publication date:
2017-08-29
Acceptance date:
2017-07-27
DOI:
EISSN:
1549-1676
ISSN:
1549-1277
Pubs id:
pubs:725048
UUID:
uuid:a8c2c0d3-9d32-4298-a7e6-9b2763f2cbb1
Local pid:
pubs:725048
Deposit date:
2017-09-04

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