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Journal article

DAMPening inflammation by modulating TLR signalling.

Abstract:

Damage-associated molecular patterns (DAMPs) include endogenous intracellular molecules released by activated or necrotic cells and extracellular matrix (ECM) molecules that are upregulated upon injury or degraded following tissue damage. DAMPs are vital danger signals that alert our immune system to tissue damage upon both infectious and sterile insult. DAMP activation of Toll-like receptors (TLRs) induces inflammatory gene expression to mediate tissue repair. However, DAMPs have also been i...

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Publication status:
Published

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Publisher copy:
10.1155/2010/672395
Journal:
Mediators of inflammation More from this journal
Volume:
2010
Pages:
1-21
Publication date:
2010-01-01
DOI:
EISSN:
1466-1861
ISSN:
0962-9351
Language:
English
Keywords:
Pubs id:
pubs:235842
UUID:
uuid:a8acac60-16ca-4672-9b16-73c15db22c07
Local pid:
pubs:235842
Source identifiers:
235842
Deposit date:
2013-11-16

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