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Variation in human genes encoding adhesion and proinflammatory molecules are associated with severe malaria in the Vietnamese

Abstract:

The genetic basis for susceptibility to malaria has been studied widely in African populations but less is known of the contribution of specific genetic variants in Asian populations. We genotyped 67 single-nucleotide polymorphisms (SNPs) in 1030 severe malaria cases and 2840 controls from Vietnam. After data quality control, genotyping data of 956 cases and 2350 controls were analysed for 65 SNPs (3 gender confirmation, 62 positioned in/near 42 malarial candidate genes). A total of 14 SNPs w...

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Publisher copy:
10.1038/gene.2012.25

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Journal:
Genes and Immunity More from this journal
Volume:
13
Issue:
6
Pages:
503-508
Publication date:
2012-09-01
DOI:
EISSN:
1476-5470
ISSN:
1466-4879
Language:
English
Keywords:
Pubs id:
pubs:334969
UUID:
uuid:a8a5734a-fdb3-40d6-a9a4-9d211b02affb
Local pid:
pubs:334969
Source identifiers:
334969
Deposit date:
2012-12-19

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