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Association of severe intrahepatic cholestasis of pregnancy with adverse pregnancy outcomes: a prospective population-based case-control study

Abstract:

Intrahepatic cholestasis of pregnancy (ICP) is a pregnancy-specific liver disease, characterized by maternal pruritus and raised serum bile acids. Our objectives were to describe the epidemiology and pregnancy complications associated with severe ICP and to test the hypothesis that adverse perinatal outcomes are increased in these women. A prospective population-based case-control study with national coverage was undertaken using the UK Obstetric Surveillance System (UKOSS). Control data for ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/hep.26617

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Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
NPEU
Role:
Author
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National Institute for Health Research More from this funder
Wellbeing of Women Charity More from this funder
Publisher:
Wiley Publisher's website
Journal:
Hepatology Journal website
Volume:
59
Issue:
4
Pages:
1482-1491
Publication date:
2014-01-01
DOI:
EISSN:
1527-3350
ISSN:
0270-9139
Source identifiers:
460240
Language:
English
Keywords:
Pubs id:
pubs:460240
UUID:
uuid:a89e2e29-d5a3-4c37-bf09-f84a49ccdef9
Local pid:
pubs:460240
Deposit date:
2014-10-15

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