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Association of severe intrahepatic cholestasis of pregnancy with adverse pregnancy outcomes: a prospective population-based case-control study

Abstract:

Intrahepatic cholestasis of pregnancy (ICP) is a pregnancy-specific liver disease, characterized by maternal pruritus and raised serum bile acids. Our objectives were to describe the epidemiology and pregnancy complications associated with severe ICP and to test the hypothesis that adverse perinatal outcomes are increased in these women. A prospective population-based case-control study with national coverage was undertaken using the UK Obstetric Surveillance System (UKOSS). Control data for ...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1002/hep.26617

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Institution:
University of Oxford
Department:
Oxford, MSD, Nuffield Department of Population Health, NPEU
Role:
Author
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Wellbeing of Women Charity More from this funder
National Institute for Health Research More from this funder
Publisher:
Wiley Publisher's website
Journal:
Hepatology Journal website
Volume:
59
Issue:
4
Pages:
1482-1491
Publication date:
2014-01-01
DOI:
EISSN:
1527-3350
ISSN:
0270-9139
URN:
uuid:a89e2e29-d5a3-4c37-bf09-f84a49ccdef9
Source identifiers:
460240
Local pid:
pubs:460240
Paper number:
4

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