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Journal article

The motor cortex shows adaptive functional changes to brain injury from multiple sclerosis.

Abstract:

Although multiple sclerosis (MS) is an inflammatory demyelinating disease, there can be substantial axonal injury and loss. We therefore hypothesized that adaptive cortical changes may contribute to limiting functional impairment, particularly in the early stages of the disease. To test our hypothesis, we used functional magnetic resonance imaging (MRI) to characterize the localization and volumes of activation in the motor cortex during simple flexion-extension finger movements. There were d...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
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Journal:
Annals of neurology
Volume:
47
Issue:
5
Pages:
606-613
Publication date:
2000-05-01
DOI:
EISSN:
1531-8249
ISSN:
0364-5134
Source identifiers:
116262
Language:
English
Keywords:
Pubs id:
pubs:116262
UUID:
uuid:a89a99f4-6c2f-47dc-9c55-48aca66b7254
Local pid:
pubs:116262
Deposit date:
2012-12-19

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