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Haematopoiesis in the era of advanced single-cell technologies

Abstract:
The molecular and functional characterization of single cells at scale has emerged as a key driver to unravel tissue biology. Thus, it is important to understand the strengths and limitations of transcriptomic approaches, molecular barcoding and functional assays used to study cellular properties at the single-cell level. Here, we review recent relevant work from the haematopoietic system and discuss how to interpret and integrate data obtained with different technologies.
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

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Publisher copy:
10.1038/s41556-018-0227-8

Authors


More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM
Subgroup:
RDM Strategic
Oxford college:
St Cross College
Role:
Author
ORCID:
0000-0002-1362-3659
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM
Subgroup:
RDM Clinical Laboratory Sciences
Role:
Author
ORCID:
0000-0002-0544-735X
Publisher:
Springer Nature Publisher's website
Journal:
Nature Cell Biology Journal website
Volume:
21
Issue:
1
Pages:
2-8
Publication date:
2019-01-02
Acceptance date:
2018-10-02
DOI:
EISSN:
1476-4679
ISSN:
1465-7392
Pubs id:
pubs:957836
URN:
uri:a8891e37-dd60-4486-8669-d47baa63e651
UUID:
uuid:a8891e37-dd60-4486-8669-d47baa63e651
Local pid:
pubs:957836
Language:
English

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