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Resorbable electrospun polydioxanone fibres modify the behaviour of cells from both healthy and diseased human tendons

Abstract:

Chronic tendinopathy in an active and ageing population represents an increasing burden to healthcare systems. Rotator cuff tendinopathy alone accounts for approximately 70 % of all shoulder pain. Tendinopathic tissue has a disorganised extracellular matrix, altered vasculature, and infiltration of fibroblasts and inflammatory cells. This altered biology may contribute to the limited success of surgical repair strategies. Electrospun resorbable scaffolds can potentially enhance endogenous rep...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.22203/eCM.v033a13

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Institution:
University of Oxford
Oxford college:
Trinity College
Role:
Author
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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
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National Institute for Health Research More from this funder
Publisher:
AO Research Institute Davos Publisher's website
Journal:
eCells and Materials Journal Journal website
Volume:
33
Pages:
169-182
Publication date:
2017-02-20
Acceptance date:
2017-01-09
DOI:
ISSN:
1473-2262
Source identifiers:
681399
Keywords:
Pubs id:
pubs:681399
UUID:
uuid:a8872821-0ffb-4a13-acd0-f9d53846d0dd
Local pid:
pubs:681399
Deposit date:
2017-02-22

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