Journal article icon

Journal article

FGF-2 promotes osteocyte differentiation through increased E11/podoplanin expression

Abstract:

E11/podoplanin is critical in the early stages of osteoblast-to-osteocyte transitions (osteocytogenesis), however, the upstream events which regulate E11 expression are unknown. The aim of this study was to examine the effects of FGF-2 on E11-mediated osteocytogenesis and to reveal the nature of the underlying signaling pathways regulating this process. Exposure of MC3T3 osteoblast-like cells and murine primary osteoblasts to FGF-2 (10 ng/ml) increased E11mRNAand protein expression (p <...>

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Publisher copy:
10.1002/jcp.26345

Authors


More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS; KIR
Role:
Author
More from this funder
Name:
Arthritis Research UK
Grant:
20413
More from this funder
Name:
Biotechnology and Biological Sciences Research Council
Grant:
BBS/E/D/20221657
More from this funder
Name:
Tertiary Education Trust Fund Nigeria
Publisher:
Wiley
Journal:
JOURNAL OF CELLULAR PHYSIOLOGY More from this journal
Volume:
233
Issue:
7
Pages:
5334-5347
Publication date:
2017-12-07
Acceptance date:
2017-11-29
DOI:
EISSN:
1097-4652
ISSN:
0021-9541
Pmid:
29215722
Keywords:
Pubs id:
pubs:844241
UUID:
uuid:a8839323-1c50-4be3-92d2-f2d4f7d52396
Local pid:
pubs:844241
Source identifiers:
844241
Deposit date:
2018-05-04

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP