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Recombinant allergen-specific antibody fragments: tools for diagnosis, prevention and therapy of type I allergy.

Abstract:

Type I allergy represents a hypersensitivity occurring in almost 20% of the population that is based on the recognition of innocuous airborn antigens (pollen, mite, mould and pet allergens) by specific immunoglobulin E. Allergic symptoms (e.g. allergic rhinitis, conjunctivitis, asthma) are caused by the release of biological mediators from effector-cells after allergen-induced crosslink of receptor-bound IgE. Here we discuss strategies to obtain recombinant allergen-specific antibody fragment...

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Publication status:
Published

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Authors


Valenta, R More by this author
Flicker, S More by this author
Eibensteiner, PB More by this author
Steinberger, P More by this author
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Journal:
Biological chemistry
Volume:
378
Issue:
8
Pages:
745-749
Publication date:
1997-08-05
EISSN:
1437-4315
ISSN:
1431-6730
URN:
uuid:a8835d58-63d3-4cde-b372-7dac6200a10d
Source identifiers:
69748
Local pid:
pubs:69748

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