Journal article
A small amount of fat does not affect piperaquine exposure in patients with malaria.
- Abstract:
-
Dihydroartemisinin-piperaquine is a new, highly effective, and well-tolerated combination treatment for uncomplicated falciparum malaria. The lipophilic characteristic of piperaquine suggests that administration together with fat will increase the oral bioavailability of the drug, and this has been reported for healthy volunteers. This pharmacokinetic study monitored 30 adult patients with uncomplicated falciparum malaria for 4.5 months to evaluate the effects of the concomitant intake of fat...
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- Publisher copy:
- 10.1128/AAC.00279-11
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Authors
Bibliographic Details
- Journal:
- Antimicrob Agents Chemother
- Volume:
- 55
- Issue:
- 9
- Pages:
- 3971-3976
- Publication date:
- 2011-09-05
- DOI:
- EISSN:
-
1098-6596
- ISSN:
-
0066-4804
- URN:
-
uuid:a87ac96c-3282-4450-ab75-d1493b9c144e
- Source identifiers:
-
163939
- Local pid:
- pubs:163939
Item Description
- Language:
- English
- Keywords:
Terms of use
- Copyright date:
- 2011
- Notes:
- PMCID: PMC3165307
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