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Analysis of the centromeric region of the human Y chromosome

Abstract:

The centromere is an important region of the chromosome which ensures correct segregation at cell division. The DNA sequences which make up human centromeres are poorly understood. An analysis of the human Y chromosome centromere DNA has therefore been undertaken. The structures of 23 yeast artificial chromosomes (YAC) clones and 4 cosmid clones have been determined and these have contributed to a map of ~7Mb of DNA which span the centromere.

The centromeric region of the human Y c...

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Institution:
University of Oxford
Department:
Life and Environmental Sciences Division

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Role:
Supervisor
Role:
Supervisor
Publication date:
1992
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Barcode:
603853069
URN:
uuid:a86ed79c-84cd-40da-8da9-3afb9acf513d
Local pid:
td:603853069
Language:
English
Subjects:

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