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Cells of the mononuclear phagocyte series differentiate into osteoclastic lacunar bone resorbing cells.

Abstract:

Although the osteoclast shares several features with other cells of the mononuclear phagocyte system (MPS), its precise cellular ontogeny is unknown, and its membership of the MPS is controversial. This study examined whether various cells of the MPS can be induced to differentiate into cells capable of the highly specialized osteoclastic function of lacunar bone resorption. We isolated mouse and rat monocytes, mouse (liver, peritoneal, alveolar, brain) tissue macrophages, and spleen and marr...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Role:
Author
Journal:
The Journal of pathology
Volume:
179
Issue:
1
Pages:
106-111
Publication date:
1996-05-05
DOI:
EISSN:
1096-9896
ISSN:
0022-3417
URN:
uuid:a86b244e-5e21-4476-a533-605d68c863c4
Source identifiers:
103924
Local pid:
pubs:103924

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