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Analysis and reporting of factorial trials: a systematic review.

Abstract:

CONTEXT: Although factorial trials have become common, standards for the analysis and reporting of such trials have not been established and, despite concerns about the possibility of unrecognized interactions between therapies in factorial trials, the magnitude of this potential problem is unknown. OBJECTIVE: To examine the rationale, methods, and analysis of randomized factorial trials. DATA SOURCES AND STUDY SELECTION: We searched MEDLINE, EMBASE, and the Cochrane Controlled Trials Registe...

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Publication status:
Published

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Publisher copy:
10.1001/jama.289.19.2545

Authors


McAlister, FA More by this author
Straus, SE More by this author
Sackett, DL More by this author
Altman, DG More by this author
Journal:
JAMA
Volume:
289
Issue:
19
Pages:
2545-2553
Publication date:
2003-05-05
DOI:
EISSN:
1538-3598
ISSN:
0098-7484
URN:
uuid:a85d665e-7d0f-46b7-8944-a598f75d7355
Source identifiers:
317915
Local pid:
pubs:317915

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